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Isaac Newton's later life : ウィキペディア英語版
Later life of Isaac Newton


During his residence in London, Newton had made the acquaintance of John Locke. Locke had taken a very great interest in the new theories of the ''Principia''. He was one of a number of Newton's friends who began to be uneasy and dissatisfied at seeing the most eminent scientific man of his age left to depend upon the meagre remuneration of a college fellowship and a professorship.
==1693==
During the period 1692–1693 Newton is known to have suffered a breakdown of nervous functioning, or a supposed ''depression'' 〔David Fisher ISBN 1-4128-0859-6 see also: (FRANK E. MANUEL 1968 )〕 (Spivak & Epstein) lasting for 18 months, as reported by Huygens.〔〔 He suffered insomnia and poor digestion, in his letters to friends showing signs of irrationality.〔Mercury Poisoning: A Probable Cause of Isaac Newton's Physical and Mental Ills - L. W. Johnson and M. L. Wolbarsht - Notes and Records of the Royal Society of London - Vol. 34, No. 1 (July 1979), pp. 1-9 (article consists of 9 pages) (JSTO ) Retrieved 28 January 2012〕
During exhumation the hair from Newton's dead body〔(© 1996-2007 Eric W. Weisstein )〕 was found to contain high levels of mercury,〔Eric Weisstein's World of Biography. (© 1996-2007 Eric W. Weisstein ) Retrieved 30 August 2006.〕 remains of desiccated hair were later found to contain four times the lead, arsenic and antimony and fifteen times mercury than in normal range samples. Two hairs contained mercury and separately lead at levels indicating chronic poisoning (Spargo & Pounds 1979).〔M.S. LESNEY- Newton's Hair (Chemistry Chronicles ) Retrieved 28 January 2012〕〔Derek Gjertsen ISBN 0-7102-0279-2〕 Symptoms of mercury poisoning exhibited by Newton were apparently tremor, severe insomnia, delusions of persecution or paranoid ideas, problems with memory, mental confusion, and withdrawal or decline from personal friendships, significant in the period of time, the deterioration of his relations with his ''protégé'' Nicholas Fatio de Duillier.〔Milo Keynes - Balancing Newton's mind: his singular behaviour and his madness of 1692–93 〕
Newton documented the first performed alchemy experiment during 1678,〔 having first obtained furnaces and chemicals in 1669.〔 Experiments with metal included analysis of taste of which there are 108 documented,〔〔 including mercury :
documented also by the scientist were similar experiments with arsenic, gold and lead.〔
Newton recorded in his notebook of experimenting with chemicals during June 1693.〔
The limited evidence for symptomatic mental illness of Newton during this period stem from ''correspondences'' (c.f. The Royal Society) revealing ''melancholia'', desire for withdrawal from relations including his good friends,insomnia, apathy, loss of appetite,''delusion of persecution'', possibly failures in memory (''amnesia''), and bipolar.〔〔http://gsappweb.rutgers.edu/centers/stigma/people.php〕 In a letter written to Samuel Pepys, Newton stated he was
on the 30th of that month Newton reported he had been ''seized by a distemper''

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